Best Western Plus Sikeston

Address

120 S Interstate Dr, Sikeston, MO 63801

Phone

(573) 481-9500

Website

bestwestern.com/en_US/book/hotel-rooms.26173.html?iata=00171890&ssob=BLBWI0003G&cid=BLBWI0003G%3Ayext%3Awebsite%3A26173

Last checked September 23, 2026. Call ahead to confirm hours.

Listing details from Overture Maps open data.